Radiological patterns of drug induced interstitial lung disease (DILD) in early phase oncology clinical trials.

CONCLUSIONS: DILD in early phase clinical trials is a toxicity of variable onset, with diverse clinical and radiological findings. Radiological findings precede clinical symptoms. The extent of the affected lung parenchyma, scored by the RMH DILD score, correlates with clinical presentation. Most events are low grade, and improve with treatment interruption which should be considered early.
PMID: 32332017 [PubMed - as supplied by publisher]

Source: Clinical Cancer Research - April 23, 2020 Category: Cancer & Oncology Authors: Terbuch A, Tiu C, Moreno Candilejo I, Scaranti M, Curcean A, Bar D, Estevez Timon M, Ameratunga M, Ang JE, Ratoff J, Minchom AR, Banerji U, de Bono JS, Tunariu N, Lopez JS Tags: Clin Cancer Res Source Type: research