Overexpression of p62 Induces Autophagy and Promotes Proliferation, Migration and Invasion of Nasopharyngeal Carcinoma Cells through Promoting ERK Signaling Pathway.

CONCLUSION: Our data establish p62 targeting ERK as potential determinant in the NPC, which supplies a new pathway to treat NPC. Furthermore, p62 is a potential biomarker which might be closely related to the tumorigenesis and metastasis in NPC.
PMID: 32329689 [PubMed - as supplied by publisher]

Source: Current Cancer Drug Targets - April 23, 2020 Category: Cancer & Oncology Authors: Wu Q, Xiang M, Wang K, Chen Z, Long L, Tao Y, Liang Y, Yan Y, Xiao Z, Qiu S, Yi B Tags: Curr Cancer Drug Targets Source Type: research