Isoprenaline induced Takotsubo syndrome: Histopathological analyses of female rat hearts.

CONCLUSIONS: The ISO female rat model of TTS is associated with higher optimum dose and lower mortality in comparison with the male TTS model. TTS presents as a singles cardiomyocyte disorder, foci concerned mainly central muscle layer with apical-basal gradient.
PMID: 32329043 [PubMed - as supplied by publisher]

Source: Cardiology Journal - April 23, 2020 Category: Cardiology Authors: Kołodzińska A, Czarzasta K, Szczepankiewicz B, Budnik M, Główczyńska R, Fojt A, Ilczuk T, Krasuski K, Borodzicz S, Cudnoch-Jędrzejewska A, Górnicka B, Opolski G Tags: Cardiol J Source Type: research