In sillico analysis, synthesis, and biological evaluation of triazole derivatives as a H1 receptor antagonist.

CONCLUSION: Finally, these derivatives were screened for H1 receptor antagonist activity using guinea pig ileum taking chlorpheniramine maleate as a standard. Most of the compounds possesses better antihistamine activity. PMID: 32316895 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/32316895?dopt=Abstract

Source: Current Drug Discovery Technologies - April 19, 2020 Category: Drugs & Pharmacology Authors: Badeliya SN, Panchal II, Panigrahi B, Patel CN Tags: Curr Drug Discov Technol Source Type: research