Caveolin-1 is critical for abdominal aortic aneurysm formation induced by angiotensin II and inhibition of lysyl oxidase

In conclusion, Cav1 appears to play a critical role in the formation of AAA and associated endoplasmic reticulum/oxidative stress presumably through the regulation of caveolae compartmentalized signals induced by Ang II.

Source: Clinical Science - December 13, 2013 Category: Biomedical Science Authors: T Takayanagi, K J. Crawford, T Kobayashi, T Obama, T Tsuji, K J. Elliott, T Hashimoto, V Rizzo, S Eguchi Source Type: research