Adult Monozygotic Twins with Hypertrophic Cardiomyopathy and Identical Disease Expression and Clinical Course

A unique clinical circumstance involving middle-aged male identical twins with obstructive hypertrophic cardiomyopathy (HC) is reported. The concordance of morphologic (i.e., phenotype) findings and clinical course between the 2 patients is remarkable, including timing of the onset and progression of heart failure due to left ventricular outflow tract obstruction, frequency of paroxysmal atrial fibrillation and beneficial response to surgical myectomy and Cox-Maze IV procedure (performed 14 days apart).
Source: The American Journal of Cardiology - Category: Cardiology Authors: Source Type: research