MiR-19b-3p facilitates the proliferation and epithelial-mesenchymal transition, and inhibits the apoptosis of intrahepatic cholangiocarcinoma by suppressing coiled-coil domain containing 6.

CONCLUSION: These results indicate that serum miR-19b-3p level is a crucial biomarker for ICC diagnosis and targeting miR-19b-3p-CCDC6 axis might be a promising strategy in ICC therapy. PMID: 32315652 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/32315652?dopt=Abstract

Source: Archives of Biochemistry and Biophysics - April 17, 2020 Category: Biochemistry Authors: Tang Y, Yang J, Wang Y, Tang Z, Liu S, Tang Y Tags: Arch Biochem Biophys Source Type: research