A novel homozygous mutation in WDR19 induces disorganization of microtubules in sperm flagella and nonsyndromic asthenoteratospermia

ConclusionsWe identifiedWDR19 as a novel pathogenic gene for male infertility caused by asthenoteratospermia in the absence of other ciliopathic phenotypes, and that patients carryingWDR19 variant can have favorable pregnancy outcomes following ICSI.
Source: Journal of Assisted Reproduction and Genetics - Category: Reproduction Medicine Source Type: research