Mitochondrial D310 D-Loop instability and histological subtypes in radiation-induced cutaneous basal cell carcinomas

Conclusions: Our results suggest that radiation-induced BCCs may be considered to be more aggressive tumors. Further studies are needed to clarify the role of mtDNA D-Loop mutations in tumors from irradiated patients.

Source: Journal of Dermatological Science - October 2, 2013 Category: Dermatology Authors: Paula Boaventura, Dina Pereira, Adélia Mendes, Rui Batista, André Ferreira da Silva, Isabel Guimarães, Mrinalini Honavar, José Teixeira-Gomes, José Manuel Lopes, Valdemar Máximo, Paula Soares Tags: Regular Articles Source Type: research