Effect of binary combinations of solvent system on permeability profiling of pure agomelatine across rat skin: A comparative study with statistically optimized polymeric nanoparticles.

CONCLUSION: The above observations concluded that binary combination of 33% PG-ethanol with 5%v/v transcutol-HP can serve as a solvent system of choice for effective transdermal delivery of agomelatine via nanoparticulate system. PMID: 32312082 [PubMed - as supplied by publisher]
Source: Drug Development and Industrial Pharmacy - Category: Drugs & Pharmacology Tags: Drug Dev Ind Pharm Source Type: research