Treatment of testicular cancer.

Treatment of testicular cancer.
Bull Cancer. 2013 Dec 6;
Authors: Droz JP, Boyle H, Culine S, Fizazi K, Fléchon A, Massard C
Abstract
Germ-cell tumours (GCTs) are the most common type of cancer in young men. Since the late 1970s, disseminated GCT have been a paradigm for curable metastatic cancer and metastatic GCTs are highly curable with cisplatin-based chemotherapy followed by surgical resection of residual masses. Patients' prognosis is currently assessed using the International Germ-Cell Consensus Classification (IGCCC) and used to adapt the burden of chemotherapy. Approximately 20% of patients still do not achieve cure after first-line cisplatin-based chemotherapy, and need salvage chemotherapy (high dose or standard dose chemotherapy). Clinical stage I testicular cancer is the most common presentation and different strategies are proposed: adjuvant therapies, surgery or surveillance. During the last three decades, clinical trials and strong international collaborations lead to the development of a consensus in the management of GCTs.
PMID: 24316884 [PubMed - as supplied by publisher]

Source: Bulletin du Cancer - December 6, 2013 Category: Cancer & Oncology Authors: Droz JP, Boyle H, Culine S, Fizazi K, Fléchon A, Massard C Tags: Bull Cancer Source Type: research