Synthesis, Molecular Docking Studies and Antibacterial Activities of Novel Monocationic Indole-benzimidazole Derivatives.
CONCLUSION: This study mainly includes the design, synthesis and optimization of indole-benzimidazole-amidine derivatives. Docking studies confirmed our results, since our most potent hit compound 36 created the necessary interactions between two chains of MRSA-PK. Further optimization can be considered to increase drug ability.
PMID: 32310051 [PubMed - as supplied by publisher]
Source: Medicinal Chemistry - Category: Chemistry Authors: Ates-Alagoz Z, Kisla MM, Goker H, Yildiz S Tags: Med Chem Source Type: research