Profile of common inflammatory markers in treatment-na ïve patients with systemic rheumatic diseases

ConclusionsESR, CRP and WBC are not always elevated in treatment-na ïve patients with SRD. Individual SRDs have a unique profile of inflammatory markers. However, routine inflammatory markers should still be interpreted with caution when diagnosing and assessing disease activity in those with SRD.Key Points•Leukocytosis and elevation of ESR and CRP are not always present in all systemic rheumatic diseases.•Inflammatory markers are often dissociated and they are not specific for disease diagnosis.•Better biomarkers, which measure disease-specific local and systemic inflammation, are needed.
Source: Clinical Rheumatology - Category: Rheumatology Source Type: research