Integration of in vitro data from three dimensionally cultured HepaRG cells and physiologically based pharmacokinetic modeling for assessment of acetaminophen hepatotoxicity

Publication date: Available online 18 April 2020Source: Regulatory Toxicology and PharmacologyAuthor(s): Chi Zhang, Qiang Zhang, Jin Li, Lin Yu, Fengxiang Li, Weiwei Li, Yujie Li, Hui Peng, Jun Zhao, Paul L. Carmichael, Yunfang Wang, Shuangqing Peng, Jiabin Guo
Source: Regulatory Toxicology and Pharmacology - Category: Toxicology Source Type: research