Expression of additional transcription factors is of prognostic value for aggressive behavior of pituitary adenomas.

CONCLUSIONS: These data suggest a more aggressive behavior of TFGA-positive adenomas if an additional TF is expressed within the tumor cells. Shorter radiographic surveillance and earlier consideration for retreatment should be recommended in these adenoma types. PMID: 32302984 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/32302984?dopt=Abstract

Source: Journal of Neurosurgery - April 16, 2020 Category: Neurosurgery Authors: Micko A, Rötzer T, Hoftberger R, Vila G, Oberndorfer J, Frischer JM, Knosp E, Wolfsberger S Tags: J Neurosurg Source Type: research