Gastric submucosal alleviated pro-inflammation cytokines mediated initial dysfunction of islets allografts.

CONCLUSIONS: Gastric submucosal would be a potential ideal site for islet transplantation in rat. Gastric submucosal might alleviate the early islet dysfunction triggered by the IL-1β and TNF-α, and which requires a low number of transplanted islets and have a good glycemic control in return. PMID: 32302641 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/32302641?dopt=Abstract

Source: Transplant Immunology - April 13, 2020 Category: Transplant Surgery Authors: Yin Z, Li J, Zheng Y, Wang S, Wang X Tags: Transpl Immunol Source Type: research