Endobronchial valve treatment of persistent alveolopleural fistulae in a patient with cystic fibrosis and empyema

Persistent air leak (PAL) is a common problem after secondary pneumothorax due to cystic fibrosis (CF). These leaks, caused by either bronchopleural or alveolopleural fistula, are associated with higher morbidity and mortality [1]. Air leaks are traditionally treated with chronic chest tube drainage, chemical pleurodesis, or autologous blood patching in non-surgical candidates [1]. However, these strategies can increase infectious risk or pleural scarring, which are associated with poorer lung transplant surgical outcomes.

Source: Journal of Cystic Fibrosis - April 17, 2020 Category: Respiratory Medicine Authors: Kale S. Bongers, Jose De Cardenas Source Type: research