Surface Contamination With Antineoplastic Drugs on Two Inpatient Oncology Units.
Surface Contamination With Antineoplastic Drugs on Two Inpatient Oncology Units.
Oncol Nurs Forum. 2020 May 01;47(3):263-272
Authors: Walton A, Bush MA, Douglas C, Allen DH, Polovich M, Spasojevic I
Abstract
OBJECTIVES: To measure surface contamination with antineoplastic drugs on inpatient oncology units and to characterize nursing staff personal protective equipment (PPE) use and factors that predict this use.
SAMPLE & SETTING: A descriptive pilot study of two inpatient oncology units at Duke University Hospital in Durham, North Carolina, administering etoposide and cyclophosphamide.
METHODS & VARIABLES: Surfaces in four patient rooms and select shared areas were swabbed with methanol, acetonitrile, and water. Samples were analyzed by liquid chromatography tandem mass spectrometry. Nursing staff (N = 27) answered questions about their demographics, PPE use, and factors that influence PPE use via online survey.
RESULTS: Contamination with cyclophosphamide and etoposide was detectable and quantifiable in 61% and 31% of surfaces tested, respectively. Nursing staff reported suboptimal use of PPE when administering, disposing, and handling excreta of patients. Workplace safety climate was predictive of PPE use.
IMPLICATIONS FOR NURSING: The potential for contamination with antineoplastic drugs in inpatient oncology units presents exposure risks for healthcare workers, patients, family memb...
Source: Oncology Nursing Forum - Category: Nursing Authors: Walton A, Bush MA, Douglas C, Allen DH, Polovich M, Spasojevic I Tags: Oncol Nurs Forum Source Type: research