Population pharmacokinetics of standard-dose meropenem in critically ill patients on continuous renal replacement therapy: a prospective observational trial.

CONCLUSIONS: The population PK model was successfully developed to describe the time course of meropenem concentrations. The hypoalbuminemia was found to be associated with higher PTA in the CRRT patients after multiple short-term infusions.
PMID: 32301057 [PubMed - as supplied by publisher]

Source: Pharmacological Reports - April 15, 2020 Category: Drugs & Pharmacology Authors: Onichimowski D, Będźkowska A, Ziółkowski H, Jaroszewski J, Borys M, Czuczwar M, Wiczling P Tags: Pharmacol Rep Source Type: research