Acute sleep deprivation elevates brain and body temperature in rats.

Acute sleep deprivation elevates brain and body temperature in rats. J Sleep Res. 2020 Apr 16;:e13030 Authors: Vishwakarma LC, Sharma B, Singh V, Jaryal AK, Mallick HN Abstract Available sleep deprivation studies lack data on simultaneous changes in hypothalamic, cortical and body temperature during sleep deprivation and recovery. Ten adult male Wistar rats chronically implanted with electroencephalogram, electro-oculogram and electromyogram electrodes for recording sleep were used in this study. Hypothalamic and cortical temperatures were measured by pre-implanted thermocouples. A radio transmitter (TA10TAF-40, DSI USA) was implanted intraperitoneally to measure body temperature. All the temperatures were measured simultaneously at 15-s intervals during baseline conditions, sleep deprivation and recovery sleep. Sleep deprivation was carried out for 24 hr by the gentle handling method; however, sleep and temperature were only recorded during the first 12 hr of deprivation. During sleep deprivation the body, hypothalamic and cortical temperatures increased significantly as compared to baseline. During recovery sleep, body and cortical temperature recovered earlier than the hypothalamic temperature. Hypothalamic temperature remained higher than the baseline values throughout 12 hr of recovery sleep. In the recovery sleep, cortical temperature decreased immediately and reached near baseline by 4 hr. We observed a quicker return of c...
Source: Journal of Sleep Research - Category: Sleep Medicine Authors: Tags: J Sleep Res Source Type: research