Impaired brain glucose metabolism and presynaptic dopaminergic functioning in a mouse model of schizophrenia

ConclusionsDopamine D2 mutant animals show reduced glucose metabolism and impaired presynaptic dopaminergic functioning, in line with reports from human studies. This mouse line may be a valuable model of schizophrenia, useful to test novel tracers for PET scanning diagnostic.

http://link.springer.com/10.1186/s13550-020-00629-x

Source: EJNMMI Research - April 16, 2020 Category: Radiology Source Type: research