Pathogenic mechanisms of a stroke-like attack elicited by epidural steroid injection therapy.

This article dissects the potential pathogenic mechanisms at a neurovascular unit. Noticeably, a schematic provides an explanation of how emboli formed by particulate steroids elicit either hemorrhagic or ischemic lesion. In addition, development of a rat model with intravertebral artery steroid injection is a proposal to address the unmet need in evaluating steroids and vascular injury in ESI. PMID: 32294038 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/32294038?dopt=Abstract

Source: Current Neurovascular Research - April 14, 2020 Category: Neurology Authors: He Z Tags: Curr Neurovasc Res Source Type: research