Immunoglobulin G and immunoglobulin G subclass concentrations differ according to sex and race

Serum immunoglobulin G (IgG) concentrations are integral to the workup of immune deficiencies and IgG4-related disease (IgG4-RD). Demographic differences in IgG concentrations are poorly described but can influence test interpretation, contribute to racial disparities in primary immunodeficiency diagnosis, and explain demographic differences in IgG concentrations in IgG4-RD.

Source: Annals of Allergy, Asthma and Immunology - March 26, 2020 Category: Allergy & Immunology Authors: Tyler Harkness, Xiaoqing Fu, Yuqing Zhang, Hyon K. Choi, John H. Stone, Kimberly G. Blumenthal, Zachary S. Wallace Source Type: research