Sensitivity and specificity of cerebrospinal fluid CXCL13 for diagnosing Lyme neuroborreliosis - a study on 1410 patients and review of the literature

The B-cell chemoattractant CXCL13 has been suggested as a cerebrospinal fluid (CSF) biomarker for Lyme neuroborreliosis (LNB). Our aim was to substantiate the value of CXCL13 in a large unselected cohort and determine a practical cut-off value to diagnose LNB.

Source: Journal of the Neurological Sciences - April 15, 2020 Category: Neurology Authors: Hannes Lintner, Petra Hochgatterer-Rechberger, Barbara Pischinger, Josef Seier, Peter Vollmann, Alexander Haushofer, Heike Rittner, Claudia Sommer, Raffi Topakian Source Type: research