A network analysis to identify pathophysiological pathways distinguishing ischaemic from non ‐ischaemic heart failure

ConclusionsPathophysiological pathways distinguishing patients with ischaemic HF from those with non ‐ischaemic HF were related to inflammation, endothelial dysfunction superoxide production, coagulation, and atherosclerosis. The five key pathway proteins identified are potential treatment targets specifically for patients with ischaemic
HF.

Source: European Journal of Heart Failure - April 2, 2020 Category: Cardiology Authors: Iziah E. Sama, Rebecca J. Woolley, Jan F. Nauta, Simon P.R. Romaine, Jasper Tromp, Jozine M. Maaten, Peter Meer, Carolyn S.P. Lam, Nilesh J. Samani, Leong L. Ng, Marco Metra, Kenneth Dickstein, Stefan D. Anker, Faiez Zannad, Chim C. Lang, J Tags: Research Article Source Type: research