[Radio-induced breast morphoea: An unrecognized complication.]

[Radio-induced breast morphoea: An unrecognized complication.]
Cancer Radiother. 2013 Dec 2;
Authors: Vigneron C, Bauer N, Waisse W, Keller A, Pop M, Clavier JB, Salze P, Noël G
Abstract
Morphoea is a localized scleroderma. Since the 1990s, it is described as a complication after irradiation for breast cancer. This complication is unrecognized and underdiagnosed. Irradiation seems to be a factor inducing an autoimmune process. Clinicians should be aware in case of an erythema in a treated area, appearing on average one year after the end of the irradiation. Histology alone can prove the diagnosis and rule out differential diagnoses: principally mastitis (carcinomatous, infectious), chronic radiodermatitis or radiation recall. Treatment of this rare complication is not consensual; it is most often topical steroids. The evolution is marked by a gradual decrease from the initial inflammation. Sclerosis persists, more or less substantially.
PMID: 24309003 [PubMed - as supplied by publisher]

Source: Cancer Radiotherapie - December 2, 2013 Category: Cancer & Oncology Authors: Vigneron C, Bauer N, Waisse W, Keller A, Pop M, Clavier JB, Salze P, Noël G Tags: Cancer Radiother Source Type: research