European Paediatric Formulation Initiative Workshop Report: Improving the Administration of Oral Liquid Medicines in Paediatrics using Dosing Syringes and Enteral Accessories.

European Paediatric Formulation Initiative Workshop Report: Improving the Administration of Oral Liquid Medicines in Paediatrics using Dosing Syringes and Enteral Accessories. Eur J Pharm Biopharm. 2020 Apr 11;: Authors: Walsh J, van Riet-Nales D, Hermans E, de Vries R, Hilton G, Blowers P, Salunke S Abstract Accurate dosing of the right medicine to the right patient is a key element of safe and efficacious pharmacotherapy, yet prone to technical challenges and human error when dosing involves the administration of small volumes of liquid medicines. For this reason, the topic has gained increased attention over the last decade from multiple stakeholder parties e.g. academia, hospital pharmacy, the medical device and pharmaceutical industry, and regulatory agencies. It is now well acknowledged that spoons and cups are not suitable for the measurement of small volumes of oral liquid medicines and that syringes are a better alternative, but syringes for parenteral use should not be used for oral dosing in order to avoid accidental parenteral delivery of oral products. However, dosing accuracy of very small volumes of liquid medicines to young children, and especially pre-term neonates, is still not sufficiently ensured. A workshop was organised in 2018 by the European Paediatric Formulation Initiative to reflect on current status and challenges (first part) and possible strategies to improve the present situation (second part). A voting...
Source: European Journal of Pharmaceutics and Biopharmaceutics - Category: Drugs & Pharmacology Authors: Tags: Eur J Pharm Biopharm Source Type: research