Extrafibrillar matrix yield stress and failure envelopes for mineralised collagen fibril arrays.

This study identified yield properties of extrafibrillar matrix using an aligned mineralised tissue. The ability to obtain yield stress data and unloading stiffness from micropillar compression tests of MTLT at the level of the mineralised collagen fibril array and downscaling these into the EM mitigates against possible errors associated with macroscopic stiffness predictions and proved to be an invaluable advantage compared to similar modelling approaches. Results may help to improve computational models that may then be used in pre-clinical testing or development of personalised treatment strategies. PMID: 32279843 [PubMed - in process]
Source: Journal of the Mechanical Behavior of Biomedical Materials - Category: Materials Science Authors: Tags: J Mech Behav Biomed Mater Source Type: research