Mechanical roles of anterograde and retrograde intestinal peristalses after feeding in a larval fish (Danio rerio).

Mechanical roles of anterograde and retrograde intestinal peristalses after feeding in a larval fish (Danio rerio). Am J Physiol Gastrointest Liver Physiol. 2020 Apr 13;: Authors: Kikuchi K, Noh H, Numayama-Tsuruta K, Ishikawa T Abstract Transport in gut is important not only for digestion, metabolism and nutrient uptake but also for microbiotic circumstance in the digestive tract, however, the effects of mixing and pumping in the intestine have not been fully clarified. Therefore, in this study, we quantitatively explored intestinal mixing and pumping represented using a dispersion coefficient and pressure rise in zebrafish larvae, which is a model organism for vertebrate digestive studies, over time by measuring transport phenomena after feeding. Here we provide the first quantitative evidence of the roles of anterograde and retrograde intestinal peristalses in the larval fish of Danio rerio after feeding in terms of digestive pumping and mixing functions by an in vivo imaging of intestinal propagation waves in the larval intestine. Peristaltic velocities in the anterior and posterior intestines change considerably after feeding for 5 hours, while the intervals and amplitudes remain almost constant. The intestinal transport is successively visualized after feeding to elimination. Moreover, the particle tracking velocimetry in the chyme leads our quantitative understanding of outstanding mixing and pumping functions in the anterior ...
Source: Am J Physiol Gastroi... - Category: Gastroenterology Authors: Tags: Am J Physiol Gastrointest Liver Physiol Source Type: research