Acute exacerbated severe form of nonalcoholic steatohepatitis leading to acute-on-chronic liver failure: A  case series

We present three patients with uncontrolled metabolic syndrome and acute-on-chronic liver failure in whom, after meticulous evaluation, the acute event was found to be a severe and exacerbated form of nonalcoholic steatohepatitis (NASH), a novel entry in the natural history of non-alcoholic fatty liver disease. This novel disease entity was described partially, 17  years before by Caldwell et al. We discuss current literature, pertinent features, and outcomes associated with a severe form of NASH, which is associated with high mortality.
Source: Indian Journal of Gastroenterology - Category: Gastroenterology Source Type: research