Current clinician perspective on non-vitamin K antagonist oral anticoagulant use in challenging clinical cases.

CONCLUSION: This expert consensus of cardiologists aimed to define management strategies for challenging cases with patients who underrepresented in pivotal trials using case examples from their routine practice. Although strong evidence is lacking, exploratory subgroup analysis of phase III pivotal trials partially informs the management of these patients. Clinical trials with higher external validity are needed to clarify areas of uncertainty. The lack of clear evidence about complex AF cases has pushed clinicians to manage patients based on clinical experience, including rare situations of off-label prescriptions.
PMID: 32281950 [PubMed - as supplied by publisher]

Source: Turk Kardiyoloji Dernegi arsivi - March 31, 2020 Category: Cardiology Authors: Türk UÖ, Acar RD, Akgün T, Emren V, Kanat S, Karacağlar E, Kepez A, Kul Ş, Özel E, Şimşek E, Yakar Tülüce S, Tülüce K, Camm AJ Tags: Turk Kardiyol Dern Ars Source Type: research