Non-increased risk of thrombosis by steroid pulse therapy in patients with lupus nephritis from the Japanese health insurance database

The risk of thrombosis in patients with systemic lupus erythematosus (SLE) is approximately 15 times as high as that in the general population [1]. A study of data derived from the Lupus in Minorities: Nature versus Nurture (LUMINA) cohort showed that a high disease activity of SLE is an independent risk factor of thrombosis [2]. Lupus nephritis (LN), especially with nephrotic syndrome, predisposes a patient to a hypercoagulability status. In addition, the use of corticosteroids (CSs) also increases the risk of thrombosis.
Source: Thrombosis Research - Category: Hematology Authors: Tags: Letter to the Editors-in-Chief Source Type: research