In vitro anticancer effects of levopimaric acid in cisplatin-resistant human lung carcinoma are mediated via autophagy, ROS-mediated mitochondrial dysfunction, cell apoptosis and modulation of ERK/MAPK/JNK signalling pathway.

CONCLUSION: The current results strongly indicate that levopimaric acid may prove to be a potential anticancer drug candidate provided further in depth studies are carried out. PMID: 32277638 [PubMed - as supplied by publisher]
Source: Journal of B.U.ON. - Category: Cancer & Oncology Tags: J BUON Source Type: research