Gynecologic cancer in pregnancy.
Gynecologic cancer in pregnancy. Gynecol Oncol. 2020 Apr 05;: Authors: Korenaga TK, Tewari KS Abstract Cancer complicates 1 in 1000 pregnancies. Multidisciplinary consensus comprised of Gynecologic Oncology, Pathology, Neonatology, Radiology, Anesthesiology, Maternal Fetal Medicine, and Social Work should be convened. Pregnancy provides an opportunity for cervical cancer screening, with deliberate delays in treatment permissible for early stage carcinoma. Vaginal delivery is contraindicated in the presence of gross lesion(s) and radical hysterectomy with lymphadenectomy at cesarean delivery is recommended. Women with locally advanced and metastatic/recurrent disease should commence treatment at diagnosis with chemoradiation and systemic therapy, respectively; neoadjuvant chemotherapy to permit gestational advancement may be considered in select cases. Most adnexal masses are benign and resolve by the second trimester. Persistent, asymptomatic, benign-appearing masses can be managed conservatively; surgery, if indicated, is best deferred to 15-20 weeks, with laparoscopy preferable over laparotomy whenever possible. Benign and malignant germ cell tumors and borderline tumors are occasionally encountered, with unilateral adnexectomy and preservation of the uterus and contralateral ovary being the rule. Epithelial ovarian cancer is exceedingly rare. Ultrasonography and magnetic resonance imaging lack ionizing radiation and can be employed to evaluate di...
Authors: Rocco D, Gregorc V, Della Gravara L, Lazzari C, Palazzolo G, Gridelli C Abstract INTRODUCTION: The development of immune checkpoint inhibitors (ICI) has represented a revolution in the treatment of non-small cell lung cancer (NSCLC) and has established a new standard of care for different settings. However, through adaptive changes, cancer cells can develop resistance mechanisms to these drugs, hence the necessity for novel immunotherapeutic agents. AREAS COVERED: This paper explores the immunotherapeutics currently under investigation in phase I clinical trials for the treatment of NSCLC as monotherap...
In this report, a total of 860 publications related to TRPM7 were analyzed. Biophysical Journal ranked top for publishing 31 papers. The United States of America had the largest number of publications (320) with a high citation frequency (11,298) and H-index (58). Chubanov V (38 publications) and Gudermann T (38 citations), who from Ludwig Maximilian University of Munich, were the most productive authors and had the greatest co-citation counts. Our study also combined the bibliometric study with a systematic review on TRPM7, highlighting the four research frontiers of TRPM7. This is the first study that demonstrated the tr...
BACKGROUND: There is a growing body of research exploring how intimate partner violence affects contraceptive decision-making, recognizing that these decisions are reflective not only of access and acceptability, but also spousal power imbalances. Unfortun...
The classes below are what I am planning to take this fall. My cGPA is 3.62 and my sGPA is 3.4. Organic chemistry 1- 3 Biology of cancer- 2 Environmental physiology- 3 Principles of exercise training- 3 I am thinking of taking a biology course rather than the exercise training class. Should I be focused on taking science courses?
Publication date: Available online 10 July 2020Source: European Journal of Surgical OncologyAuthor(s): Philip H. Pucher, Saqib A. Rahman, Robert C. Walker, Ben L. Grace, Andrew Bateman, Tim Iveson, Andrew Jackson, Charlotte Rees, James P. Byrne, Jamie J. Kelly, Fergus Noble, Timothy J. Underwood
Publication date: Available online 9 July 2020Source: European Journal of Surgical OncologyAuthor(s): Rami Rhaiem, Tullio Piardi, Ahmad Tashkandi, Reza Kianmanesh
CONCLUSIONS: Financial and cultural issues were important hindrances to breast cancer screening in African American women. These findings highlight the importance of affordable health care for preventive health services as well as the relevance of culturally embedded issues to health, while the MQS accentuates the need for more rigorous research articles. Breast cancer screening interventions in this population should attend to barriers identified in this review. PMID: 32641257 [PubMed - as supplied by publisher]
Publication date: Available online 9 July 2020Source: Diagnostic and Interventional ImagingAuthor(s): R. Rella, E. Bufi, P. Belli, F. Petta, T. Serra, V. Masiello, A.R. Scrofani, R. Barone, A. Orlandi, V. Valentini, R. Manfredi
ConclusionsA high intake of fruits and berries and vegetables, in particular leaf vegetables, are associated with a decreased risk of developing AAA.
About 10 percent of Black, Hispanic and Latino participants in a Philadelphia study of pregnant women had been exposed to the coronavirus, compared with 2 percent of white participants.
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