HIV-1 Broadly Neutralizing Antibodies Take the Road Less Traveled, and That Makes All the Difference.

HIV-1 Broadly Neutralizing Antibodies Take the Road Less Traveled, and That Makes All the Difference. Cell Host Microbe. 2020 Apr 08;27(4):487-488 Authors: Roskin K, Spearman P Abstract Broadly neutralizing antibodies (bnAbs) against HIV-1 provide critical insights into co-evolution between the virus and human B cell responses. In this issue of Cell Host & Microbe, Shen et al. (2020) describe a rare mutation in an antibody lineage targeting the fusion peptide of HIV-1 envelope creating a critical bifurcation, with only one path leading to bnAb development. PMID: 32272069 [PubMed - in process]
Source: Cell Host and Microbe - Category: Microbiology Authors: Tags: Cell Host Microbe Source Type: research
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