Taking the STING Out of Sepsis?

Taking the STING Out of Sepsis?
Cell Host Microbe. 2020 Apr 08;27(4):491-493
Authors: Vandewalle J, Vanderhaeghen T, Beyaert R, Libert C
Abstract
In this issue of Cell Host & Microbe, Zhang et al. use a sepsis mouse model to show that macrophage-specific release of coagulation factor F3 depends on pathogen detection and responses mediated by TMEM173/STING. The therapeutic power of targeting TMEM173/STING-F3 is evident in mice, but will it penetrate the sepsis bedside?
PMID: 32272071 [PubMed - in process]

Source: Cell Host and Microbe - April 7, 2020 Category: Microbiology Authors: Vandewalle J, Vanderhaeghen T, Beyaert R, Libert C Tags: Cell Host Microbe Source Type: research