Targeting Plasmepsins-An Achilles' Heel of the Malaria Parasite.

Targeting Plasmepsins-An Achilles' Heel of the Malaria Parasite.
Cell Host Microbe. 2020 Apr 08;27(4):496-498
Authors: Burrows JN, Soldati-Favre D
Abstract
Recently, two Plasmodium aspartyl proteases were identified as druggable targets impacting parasite survival. In this issue of Cell Host & Microbe, Favuzza et al. describe the optimization of a compound series acting on both targets, heralding the prospect of a new class of antimalarials for clinical studies.
PMID: 32272073 [PubMed - in process]

Source: Cell Host and Microbe - April 7, 2020 Category: Microbiology Authors: Burrows JN, Soldati-Favre D Tags: Cell Host Microbe Source Type: research