PrEP for HIV Prevention: Evidence, Global Scale-up, and Emerging Options.
PrEP for HIV Prevention: Evidence, Global Scale-up, and Emerging Options.
Cell Host Microbe. 2020 Apr 08;27(4):502-506
Authors: Celum C, Baeten J
Abstract
Antiretroviral pre-exposure prophylaxis (PrEP) for the prevention of HIV infection was demonstrated to be efficacious and safe earlier this decade from pivotal studies using oral emtricitabine-tenofovir disoproxil fumarate. Regulatory approval and normative guidance, now for almost 70 countries worldwide, has followed. Demonstration projects have shown high uptake and population-level HIV reductions, highlighting the need for simplifying delivery and reducing current barriers to access and persistence. A portfolio of additional, next-generation PrEP formulations, currently under testing, if effective, will offer users choice and likely increase coverage and impact.
PMID: 32272075 [PubMed - in process]
Source: Cell Host and Microbe - Category: Microbiology Authors: Celum C, Baeten J Tags: Cell Host Microbe Source Type: research