Nasal delivery of a CRMP2-derived CBD3 adenovirus improves cognitive function and pathology in APP/PS1 transgenic mice

Calcium dysregulation is a key pathological event in Alzheimer ’s disease (AD). In studying approaches to mitigate this calcium overload, we identified the collapsin response mediator protein 2 (CRMP2), an axon...

Source: Molecular Brain - April 9, 2020 Category: Neuroscience Authors: Baochang Qi, Yu Yang, Yingying Cheng, Di Sun, Xu Wang, Rajesh Khanna and Weina Ju Tags: Research Source Type: research