Epstein-Barr virus-positive plasmacytoma in immunocompetent patients: a diagnostic dilemma.

We reported the clinicopathologic and immunophenotypic findings of four patients with EBV-positive plasmacytomas (three cases of extramedullary plasmacytomas, one case of solitary plasmacytoma of bone) with immunocompetent status. These tumors were characterized by a diffuse proliferation of mature appearing plasma cells, which were diffusely positive for EBV encoded RNA (EBER) by in situ hybridization. All the four patients were alive with no evidence of disease at last follow-up.
PMID: 32269699 [PubMed]

Source: International Journal of Clinical and Experimental Pathology - April 10, 2020 Category: Pathology Authors: He L, Li Z, Fan X, Shi Q, Wu H, Chen J Tags: Int J Clin Exp Pathol Source Type: research