Systematic Review and Meta-analysis on Colorectal Cancer Findings on Colonic Evaluation After CT-Confirmed Acute Diverticulitis

BACKGROUND: CT findings of acute diverticulitis can overlap with features of malignancy, and current guidelines recommend colonic evaluation after acute diverticulitis. However, the benefits of routine colonic evaluation have been questioned. OBJECTIVE: We review 30 studies, composed of 29,348 subjects, to evaluate the role of routine colonic evaluation after CT-proven acute diverticulitis. DATA SOURCES: Medline, EMBASE, and the Cochrane Library were searched for articles published up to July 2018 to identify all relevant articles. STUDY SELECTION: A combination of both Medical Subject Headings and non-Medical Subject Headings key terms using Boolean operators were used on Medline, including colonic neoplasms, colorectal cancer, colon cancer, colonic cancer, colonoscopy, and diverticulitis. Any randomized or nonrandomized, English-language article that specifically analyzed incidence of colorectal cancer after performing colonoscopy in patients with previous diverticulitis was included. MAIN OUTCOME MEASURES: The desired outcome was to evaluate for incidence of colonic malignancy in cases of acute colonic diverticulitis. Subgroup analyses for incidence of malignancy in uncomplicated and complicated diverticulitis, and Asian population studies were also performed. RESULTS: Findings of colonic malignancy occurred in 1.67% (95% CI, 1.24–2.14) of patients with CT-diagnosed diverticulitis. The risk of malignancy in cases with uncomplicated diverticulitis was...
Source: Diseases of the Colon and Rectum - Category: Gastroenterology Tags: Current Status Reviews Source Type: research

Related Links:

FRIDAY, Aug. 9, 2019 -- Although colonoscopy screens for cancer, it can also uncover a common condition called diverticulosis. This is when one or more pockets develop in the colon wall, often in the large bowel. These pockets occur over time,...
Source: Drugs.com - Daily MedNews - Category: General Medicine Source Type: news
Endoscopy DOI: 10.1055/a-0919-4803 Background The post-colonoscopy colorectal cancer (PCCRC) rate is a key quality indicator for colonoscopy. Previously published PCCRC rates have been difficult to compare owing to differences in methodology. The primary aim of this study was to compare Danish PCCRC rates internationally and to calculate Danish PCCRC rates using the World Endoscopy Organization (WEO) consensus method for future comparison. The secondary aim was to identify factors associated with PCCRC. Methods National registries were used to examine the risk of PCCRC. The Danish 3-year rate of PCCRC (PCCR...
Source: Endoscopy - Category: Gastroenterology Authors: Tags: Original article Source Type: research
Purpose: Residual faecal material, poor insufflation, complex diverticular disease, segmental colitis and spasm can mimic tumours on diagnostic Computed Tomography (CT). We aim to evaluate the diagnostic accuracy of focused ultrasound (US) in characterisation of colonic pathology in patients following abdominal CT and CT colonography (CTC). US is used in our service to allow patients to proceed direct to surgery without confirmatory colonoscopy.
Source: Clinical Radiology - Category: Radiology Authors: Source Type: research
ConclusionDespite the advancement in visualization of anatomy with CT scan and laparoscopic appendicectomy there is still a role for screening colonoscopy in patients greater than 50 years of age with appendicitis particularly if they have associated bowel symptoms or risk factors for CRC.
Source: Annals of Medicine and Surgery - Category: General Medicine Source Type: research
ConclusionFor colon stenosis suspected of malignant disease, it was thought that resection by inserting SEMS should be taken into consideration even for benign disease as a result.
Source: International Journal of Surgery Case Reports - Category: Surgery Source Type: research
We may now have an explanation for the people who experience brain fog with probiotic use. We already know that intolerance to prebiotic fibers within the first 60 minutes of ingestion have small intestinal bacterial overgrowth, SIBO. If you experience excessive gas, bloating, abdominal discomfort, or diarrhea within the first hour of consuming, say, inulin, a raw white potato, or legumes, it is virtually certain that you have SIBO that must be addressed if you desire full recovery of health. Recall that uncorrected SIBO can account for fibromyalgia, IBS, restless leg syndrome, psoriasis, and marked long-term potential for...
Source: Wheat Belly Blog - Category: Cardiology Authors: Tags: News & Updates Source Type: blogs
CONCLUSION: Our study highlights that young patients who have an index case of uncomplicated diverticulitis with no other risk factors or complications may not gain further benefit from routine colonoscopy as once traditionally thought. (Acta gastroenterol. belg., 2016, 79, 435-439). PMID: 28906213 [PubMed - in process]
Source: Acta Gastro-Enterologica Belgica - Category: Gastroenterology Tags: Acta Gastroenterol Belg Source Type: research
Objective: To investigate the association between diverticulitis and colon cancer in a large, nationwide cohort study. Background: Diverticulitis is a common disease, especially in the Western world. Previous articles have investigated the association between diverticulitis and colon cancer with inconclusive results. Methods: We conducted a population-based cohort study based on longitudinal Danish national registers with data from the period 1995 to 2012. Data were extracted from comprehensive Danish national registers containing information from both public and private hospitals. Patients with diverticulitis were ident...
Source: Annals of Surgery - Category: Surgery Tags: Original Articles Source Type: research
CONCLUSION: Our study highlights that young patients who have an index case of uncomplicated diverticulitis with no other risk factors or complications may not gain further benefit from routine colonoscopy as once traditionally thought. (Acta gastroenterol. belg., 2016, 79, 435-439). PMID: 28209102 [PubMed - in process]
Source: Acta Gastro-Enterologica Belgica - Category: Gastroenterology Tags: Acta Gastroenterol Belg Source Type: research
ConclusionRoutine interval colonoscopy following an episode of conservatively managed uncomplicated diverticulitis may not be necessary. Interval colonoscopy is still indicated in patients with complicated diverticulitis. Further collaborative study across different institutions may be warranted to gain better statistical significance.
Source: International Journal of Colorectal Disease - Category: Gastroenterology Source Type: research
More News: Cancer | Cancer & Oncology | Colon Cancer | Colonoscopy | Colorectal Cancer | Databases & Libraries | Diverticular Disease | Gastroenterology | Study