The Impact of Anastomotic Leakage on Long-term Function After Anterior Resection for Rectal Cancer
This study aimed to evaluate how anastomotic leakage following anterior resection for rectal cancer influences defecatory, urinary, and sexual function.
DESIGN:
In this retrospective population-based cohort study, patients were identified through the Swedish Colorectal Cancer Registry, which was also used for information on the exposure variable anastomotic leakage and covariates.
SETTINGS:
A nationwide register was used for including patients.
PATIENTS:
All patients undergoing anterior resection for rectal cancer in Sweden from April 2011 to June 2013 were included.
MAIN OUTCOME MEASURES:
Outcome was any defecatory, sexual, or urinary dysfunction, assessed 2 years after surgery by a postal questionnaire. The association between anastomotic leakage and function was assessed in multivariable logistic and linear regression models, with adjustment for confounding.
RESULTS:
Response rate was 82%, resulting in 1180 included patients. Anastomotic leakage occurred in 7.5%. A permanent stoma was more common among patients with leakage (44% vs 9%; p
Source: Diseases of the Colon and Rectum - Category: Gastroenterology Tags: Original Contributions: Colorectal Cancer Source Type: research
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