Corticosteroid treatment of patients with coronavirus disease 2019 (COVID-19).
CONCLUSIONS: Corticosteroids are widely used when treating patients with COVID-19, but we found no association between therapy and outcomes in patients without acute respiratory distress syndrome. An existing HBV infection may delay SARS-CoV-2 clearance, and this association should be further investigated. PMID: 32266987 [PubMed - as supplied by publisher]
Authors: Shi YQ, Qi WF, Kong CY Abstract Rheumatoid arthritis (RA), which normally manifests as a multi‑joint inflammatory reaction, is a common immunological disease in clinical practice. However, the pathogenesis of RA has not yet been fully elucidated. Rituximab (RTX) is an effective drug in the treatment of RA, however its therapeutic efficacy and mechanism of action require further investigation. Thus, the present study aimed to screen the candidate key regulatory genes and explain the potential mechanisms of RA. Gene chips of RA and normal joint tissues were analyzed and, gene chips of RTX before and after ...
In conclusion, TCGA classification based on a Chinese population is the same as TCGA typing based on a European population in terms of proportion and clinical characteristics, but there are differences in gene amplification and gene mutation. ACRG molecular classification could be performed by IHC analysis and may be a valuable independent prognostic marker for patients with GC. PMID: 32468041 [PubMed - as supplied by publisher]
This article proposes strategies to ensure the ongoing effectiveness, efficiency and engagement of lectures transitioning from face-to-face to online delivery. Cognitive learning theory, strategies to promote learner engagement and minimise distraction, and examples of software affordances to support active learning during the lecture are proposed. This enables lecturers to navigate the challenges of lecturing in an online environment and plan fruitful online lectures during this disruptive time. These suggestions will therefore enable HPE to better meet the existing and future needs of regional, rural and remote learners ...
Publication date: Available online 29 May 2020Source: The Lancet Respiratory MedicineAuthor(s): James H Hull, Julie K Lloyd, Brendan G Cooper
Publication date: Available online 29 May 2020Source: The Lancet Respiratory MedicineAuthor(s): Talha Khan Burki
Publication date: Available online 29 May 2020Source: Nutrition, Metabolism and Cardiovascular DiseasesAuthor(s): Alessandro Mantovani, Christopher D. Byrne, Ming-Hua Zheng, Giovanni Targher
Publication date: Available online 29 May 2020Source: Nutrition, Metabolism and Cardiovascular DiseasesAuthor(s): Elisabetta Torlone, Camilla Festa, Gloria Formoso, Marina Scavini, Maria Angela Sculli, Elena Succurro, Laura Sciacca, Paolo Di Bartolo, Francesco Purrello, Annunziata Lapolla
New York City, the epicenter of the coronavirus pandemic in the U.S., is on track to slowly reopen. However, other states throughout the country are still experiencing increases in coronavirus cases. Tom Hanson reports.
Families across England will finally be able to see their elderly relatives again tomorrow, as millions of vulnerable people 'shielding' are allowed to spend time outdoors as the lockdown is eased.
As if Covid-19 wasn't enough to worry about, now there is violence and civil unrest in big cities across the country. What is happening? It's like LA 92 again.