Childhood type 1 diabetes: an environment-wide association study across England
Conclusions/interpretationOur analysis identifies a range of demographic and environmental factors associated with type 1 diabetes in children in England.
Publication date: Available online 30 May 2020Source: Journal of the Formosan Medical AssociationAuthor(s): Jia-Kang Wang, Tzu-Lun Huang, Pei-Yao Chang
Publication date: Available online 30 May 2020Source: Diabetes &Metabolic Syndrome: Clinical Research &ReviewsAuthor(s): Hema S. Gopalan, Anoop Misra
Publication date: Available online 30 May 2020Source: Diabetes &Metabolic Syndrome: Clinical Research &ReviewsAuthor(s): Sachin Atre, Sona Deshmukh, Manjusha Kulkarni
Publication date: 15 September 2020Source: Journal of Ethnopharmacology, Volume 259Author(s): Junnan Ma, Xianglong Meng, Yi Liu, Cheng Yin, Tong Zhang, Piao Wang, Yong-Ki Park, Hyo Won Jung
Osborne H Abstract The calcium-sensing receptor (CaSR) is a class C G protein-coupled receptor that responds to multiple endogenous agonists and allosteric modulators, including divalent and trivalent cations, L-amino acids, γ-glutamyl peptides, polyamines, polycationic peptides, and protons. The CaSR plays a critical role in extracellular calcium (Ca2+ o) homeostasis, as demonstrated by the many naturally occurring mutations in the CaSR or its signaling partners that cause Ca2+ o homeostasis disorders. However, CaSR tissue expression in mammals is broad and includes tissues unrelated to Ca2+ o homeostasis, ...
Publication date: July 2020Source: American Heart Journal, Volume 225Author(s): Angela Lowenstern, Shuang Li, Salim S. Virani, Ann Marie Navar, Zhuokai Li, Jennifer G. Robinson, Veronique L. Roger, Anne C. Goldberg, Andrew Koren, Michael J. Louie, Eric D. Peterson, Tracy Y. Wang
Diabetes Core Update is a monthly podcast that presents and discusses the latest clinically relevant articles from the American Diabetes Association’s four science and medical journals – Diabetes, Diabetes Care, Clinical Diabetes, and Diabetes Spectrum. Each episode is approximately 20 minutes long and presents 5-6 recently published articles from ADA journals. Intended for practicing physicians and health care professionals, Diabetes Core Update discusses how the latest research and information published in journals of the American Diabetes Association are relevant to clinical practice and can be applied in a ...
DIABETES type 2 symptoms include unexplained weight loss, tiredness, and passing more urine than normal. But you could also be at risk of high blood sugar if you develop this subtle sign in your mouth, it's been revealed. Could you be at risk of diabetes?
Conclusions: Within our study population, pemphigus predominately affected females, and the most common clinical variant was PV, a subtype that frequently occurs in middle-aged individuals. MCP was the most common clinical pattern. Although MCP and higher doses of corticosteroids were needed to control pemphigus, they did not seem to influence the prognosis. PMID: 32467679 [PubMed]
Eun Jin Yoo1, Hwan Hee Lee1, Byeong Jin Ye1, Jun Ho Lee1, Chae Young Lee1, Hyun Je Kang1, Gyu Won Jeong1, Hyun Park1, Sun Woo Lim2, Whaseon Lee-Kwon1, Hyug Moo Kwon1* and Soo Youn Choi1* 1School of Life Sciences, Ulsan National Institute of Science and Technology, Ulsan, South Korea 2Transplantation Research Center, Catholic University of Korea, Seoul, South Korea TonEBP is a key transcriptional activator in macrophages with an M1 phenotype. High expression of TonEBP is associated with many inflammatory diseases. Heme oxygenase-1 (HO-1), a stress-inducible protein, is induced by various oxidative and inflammator...