Scleredema of Buschke associated with lichen sclerosus: Three cases
We report three patients who developed lichen sclerosus et atrophicus superimposed on skin involved by scleredema adultorum of Buschke. Although the association of lichen sclerosus et atrophicus with scleredema adultorum of Buschke could be coincidental, both diseases could be considered part of the spectrum of sclerodermoid disorders with common underlying pathogenetic mechanisms; which could explain the sequential or simultaneous occurrence of both lesions in our patients.
Conclusion: SYK activates TGF-β1/Smad3 signaling, while miR-136 inhibits TGF-β1/Smad3 signaling mediating tubular epithelial cell fibrosis by down-regulating SYK. PMID: 32441195 [PubMed - in process]
CONCLUSIONS: Medicaid funding and targeted grant funding were associated with addiction treatment capacity in health centers. PMID: 32438889 [PubMed - as supplied by publisher]
CONCLUSIONS: The STEP program evaluates the efficacy and safety of semaglutide 2.4 mg subcutaneously once weekly in a broad population. The trials will provide insights on WM in people with obesity with and without type 2 diabetes and on long-term follow-up. PMID: 32441473 [PubMed - in process]
The name and the email information of one of the author on the original published version of this article were presented incorrectly. The author name“Hamdi Brham” with email information Hamdi.firstname.lastname@example.org should have been presented as“Hamdi Braham” with the correct email information, Hamdi.email@example.com.
Authors: Padoan R, Felicetti M, Gatto M, Polito P, Doria A, Schiavon F Abstract OBJECTIVES: The burden of hypogammaglobulinaemia following rituximab (RTX) treatment in rheumatic diseases has not been fully elucidated yet. Our aim was to evaluate the frequency and predictors of hypogammaglobulinaemia in patients affected by ANCA-associated vasculitis (AAV) and connective tissue diseases (CTD). METHODS: We retrospectively reviewed prospectively collected data of patients receiving RTX. Immunoglobulins (Ig) levels and lymphocyte subsets were recorded at RTX administration and 3-6 months later. We assessed frequenc...
Publication date: Available online 23 May 2020Source: Diabetes &Metabolic Syndrome: Clinical Research &ReviewsAuthor(s):
Publication date: Available online 23 May 2020Source: Diabetes &Metabolic Syndrome: Clinical Research &ReviewsAuthor(s): Awadhesh Kumar Singh, Ritesh Gupta, Anoop Misra
Publication date: Available online 22 May 2020Source: Diabetes &Metabolic Syndrome: Clinical Research &ReviewsAuthor(s): Victoria E. Sanborn, M. Andrea Azcarate-Peril, John Gunstad
Publication date: Available online 22 May 2020Source: Pharmacological ResearchAuthor(s): Valencia Fernandes, Mamta Choudhary, Ashutosh Kumar, Shashi Bala Singh
Publication date: August 2020Source: Biomedicine &Pharmacotherapy, Volume 128Author(s): Maede Hasanpour, Milad Iranshahy, Mehrdad Iranshahi