Cancers, Vol. 12, Pages 918: Trends in Treatment and Survival of Gallbladder Cancer in the Netherlands; Identifying Gaps and Opportunities from a Nation-Wide Cohort

In conclusion, survival of GBC remains poor. Radical surgery and palliative chemotherapy appear to improve prognosis but remain under-utilized.
Source: Cancers - Category: Cancer & Oncology Authors: Tags: Article Source Type: research

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According to this study, green spaces are restorative and boost attention, while viewing concrete worsens attention during tasks. Finding a forest therapy guide The Association of Nature and Forest Therapy trains and certifies forest therapy guides across the world. Guides help people forge a partnership with nature through a series of invitations that allow participants to become attentive to the forest, to deepen their relationship with nature, and allow the natural world to promote healing and well-being. Ultimately, guides support what the forests have to offer us, inviting participants into practices that deepen physi...
Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Exercise and Fitness Health Mental Health Stress Source Type: blogs
In this study, 10 GBC patients and 30 patients with gallstones were admitted to our hospital. Patients with gallstones were divided into 3 groups according to the follow-up time, involving 10 patients with follow-up period of 1–3 years (GS3 group), 10 patients with follow-up period of 5–10 years (GS5 group), and 10 patients with follow-up period of more than 10 years (GS10 group). Tumor and para-tumor tissues of GBC patients, and gallbladder tissues of gallstone patients were collected. RNA sequencing was performed on the 50 samples. Besides, 1,704 differentially expressed genes (DEGs) were identified in tumors...
Source: Frontiers in Oncology - Category: Cancer & Oncology Source Type: research
Analytical ChemistryDOI: 10.1021/acs.analchem.0c00275
Source: Analytical Chemistry - Category: Chemistry Authors: Source Type: research
Recently, FAM83H was reported to have roles in cancer progression in conjunction with oncogenic molecules such as MYC and b-catenin. Moreover, the data from the public database indicates a molecular relationsh...
Source: Diagnostic Pathology - Category: Pathology Authors: Tags: Research Source Type: research
Conclusion: The diagnostic efficiency for EHCC of MUC3A is obviously superior to CA19-9 and CEA, and a high level of serum MUC3A indicates a poor prognosis, therefore, MUC3A can be used as a potential diagnostic and prognostic biomarker for EHCC.
Source: The Saudi Journal of Gastroenterology - Category: Gastroenterology Authors: Source Type: research
Gallbladder cancer rates were found to be low and similar among both patients with and without gallbladder polyps, according to a recent study.
Source: CancerNetwork - Category: Cancer & Oncology Authors: Source Type: news
This study aimed to investigate the prognostic value of tumour location in T2 gallbladder cancer, and to clarify the adequate extent of surgical resection. METHODS: Clinical data from patients who underwent surgery for gallbladder cancer were collected from 14 hospitals in Korea, Japan, Chile and the USA. Survival and risk factor analyses were conducted. RESULTS: Data from 937 patients were available for evaluation. The overall 5-year disease-free survival rate was 70·6 per cent, 74·5 per cent for those with T2a and 65·5 per cent among those with T2b tumours (P = 0·028). Re...
Source: The British Journal of Surgery - Category: Surgery Authors: Tags: Br J Surg Source Type: research
This study reviewed the literature on obesity and pancreatobiliary disease in terms of epidemiology and mechanism. PMID: 32448855 [PubMed - in process]
Source: Korean J Gastroenter... - Category: Gastroenterology Authors: Tags: Korean J Gastroenterol Source Type: research
CONCLUSIONS: Bioinformatic and experimental analyses reveal that TFAP2A plays a vital role in ferroptosis and hence is a potential therapeutic target for GBC treatment. PMID: 32432738 [PubMed - in process]
Source: European Review for Medical and Pharmacological Sciences - Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research
Patients with gallbladder cancer have worse overall survival compared to those with other anatomic biliary tract cancer primary sites of origin and should be considered as a stratification factor in clinical trials. Landmark survival rates allow for adjusted prognosis prediction for patients with advanced biliary tract cancer who survive for some time.
Source: Journal of Hepatology - Category: Gastroenterology Authors: Source Type: research
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