Safety and efficacy of tranexamic acid with epinephrine for prevention of blood loss following surgery for trochanteric femoral fractures.

CONCLUSION: Local administration of TXA with DEP reduced blood loss and limited the need for blood transfusions after surgery for trochanteric femoral fracture without increasing the risk of perioperative complications. Our study indicates that the local administration of TXA/DEP is safe and more effective than the administration of TXA alone in treating trochanteric femoral fractures. LEVEL OF EVIDENCE: Level III, Therapeutic study. PMID: 32254027 [PubMed - in process]

https://www.ncbi.nlm.nih.gov/pubmed/32254027?dopt=Abstract

Source: Acta Orthopaedica et Traumatologica Turcica - February 29, 2020 Category: Orthopaedics Authors: Xu X, Xie L, Yu H, Hu Y Tags: Acta Orthop Traumatol Turc Source Type: research