Glutamateric contribution to probabilistic reasoning and jumping-to-conclusions in schizophrenia: a double blind, randomized experimental trial.

Impaired probabilistic reasoning and the jumping-to-conclusions reasoning bias (JTC) are hallmark features of schizophrenia (SCZ), yet the neuropharmacological basis of these deficits remain unclear. Here we test the hypothesis that glutamatergic neurotransmission specifically contributes to JTC and impaired probabilistic reasoning in SCZ.

Source: Biological Psychiatry - April 7, 2020 Category: Psychiatry Authors: Strube Wolfgang, Marshall Louise, Quattrocchi Graziella, Little Simon, Cimpianu Camelia Lucia, Ulbrich Miriam, Schneider-Axmann Thomas, Falkai Peter, Hasan Alkomiet, Bestmann Sven Tags: Archival Report Source Type: research