Exercise-Induced Cognitive Improvement Is Associated with Sodium Channel-Mediated Excitability in APP/PS1 Mice.

This study suggests that exercise improves cognition and neural activity by altering the numbers and distribution of hippocampal Nav in APP/PS1 mice. Long-term treadmill exercise, for about 24 weeks, starting in the preclinical stage, is a promising therapeutic strategy for preventing AD and halting its progress. PMID: 32256560 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/32256560?dopt=Abstract

Source: Neural Plasticity - April 8, 2020 Category: Neurology Authors: Tan YX, Liu GC, Chen HL, Lu MN, Chen B, Hu T, Zhang L, Mao R, Li S, Mei R, Wang XY, Xiyang YB Tags: Neural Plast Source Type: research