Short-term organoid culture for drug sensitivity testing of high-grade serous carcinoma.

CONCLUSIONS: Short duration organoid culture of MCS from HGSOC malignant effusions can be used as a platform for empiric drug sensitivity testing. These ex vivo models may be helpful in screening new or existing therapeutic agents prior to individualized treatment options.
PMID: 32253045 [PubMed - as supplied by publisher]

Source: Gynecologic Oncology - April 2, 2020 Category: Cancer & Oncology Authors: Chen H, Gotimer K, De Souza C, Tepper CG, Karnezis AN, Leiserowitz GS, Chien J, Smith LH Tags: Gynecol Oncol Source Type: research